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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602006020071D1 (en) * | 2005-12-21 | 2011-03-24 | Univ Louvain | Isolated liver stem cells |
US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
WO2012005690A1 (en) * | 2010-07-07 | 2012-01-12 | Massachusetts Institute Of Technology | Methods of reconstituting human hepatocytes and human hematopoietic cells in non-human mammals |
WO2012020101A1 (en) * | 2010-08-12 | 2012-02-16 | Alexander Gerbes | Method for producing cells having characteristics of hepatocytes |
EP2806879B1 (en) | 2012-01-25 | 2019-03-06 | Université Catholique de Louvain | Compositions and methods for cell transplantation |
EP2690174B1 (en) * | 2011-03-25 | 2018-12-26 | Kyoto University | Method for producing epithelial stem cells |
WO2013047720A1 (en) * | 2011-09-30 | 2013-04-04 | 公立大学法人横浜市立大学 | Method for inducing hepatocellular variation, and production method for chimeric non-human animal having humanized liver |
US20160129047A1 (en) | 2013-07-05 | 2016-05-12 | Université Catholique de Louvain | Conditioned medium from human adult liver stem cells and its use in the treatment of liver disorders |
WO2016001839A1 (en) * | 2014-06-30 | 2016-01-07 | Stempeutics Research Pvt. Ltd. | Management of liver disease using pooled mesenchymal stromal cells |
EP3307874A4 (en) * | 2015-06-12 | 2019-04-24 | Agency For Science, Technology And Research | Derivation of hepatic stem cells and mature liver cell types and uses thereof |
JP2019516391A (en) * | 2016-05-24 | 2019-06-20 | リ,アルバートLI,Albert | Novel cell culture method, cell culture system and use thereof |
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6069005A (en) † | 1991-08-07 | 2000-05-30 | Albert Einstein College Of Medicine Of Yeshwa University | Hapatoblasts and method of isolating same |
US5869243A (en) | 1996-03-05 | 1999-02-09 | Rhode Island Hospital | Immortalized hepatocytes |
US6774120B1 (en) * | 1999-06-01 | 2004-08-10 | Sarah Ferber | Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues |
US20020039786A1 (en) | 2000-01-19 | 2002-04-04 | Reid Lola M. | Liver tissue source |
US6617152B2 (en) | 2001-09-04 | 2003-09-09 | Corning Inc | Method for creating a cell growth surface on a polymeric substrate |
AU2004236573B2 (en) | 2003-05-12 | 2009-10-22 | Sarah Ferber | Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues |
KR20060036933A (en) | 2003-10-07 | 2006-05-02 | 바이오마스터 인코포레이티드 | Cell differentiation of adipose-derived precursor cells |
DE602006020071D1 (en) * | 2005-12-21 | 2011-03-24 | Univ Louvain | Isolated liver stem cells |
Publication number | Publication date |
---|---|
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PL2281875T3 (en) | 2018-08-31 |
Publication | Publication Date | Title | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dabeva et al. | Proliferation and differentiation of fetal liver epithelial progenitor cells after transplantation into adult rat liver | |||||||||||||
Stéphenne et al. | Sustained engraftment and tissue enzyme activity after liver cell transplantation for argininosuccinate lyase deficiency | |||||||||||||
Duncan et al. | Stem cells and liver regeneration | |||||||||||||
JP5068901B2 (en) | Human liver progenitor cells | |||||||||||||
Stock et al. | The generation of hepatocytes from mesenchymal stem cells and engraftment into murine liver | |||||||||||||
Najimi et al. | Adult-derived human liver mesenchymal-like cells as a potential progenitor reservoir of hepatocytes? | |||||||||||||
ES2292772T3 (en) | Liver engrafting cells, analysis, and their uses. | |||||||||||||
Nahmias et al. | Integration of technologies for hepatic tissue engineering | |||||||||||||
US20080206343A1 (en) | Hepatocytes and Chondrocytes from Adherent Placental StemCells; And CD34+ ,CD45- Placental Stem Cell-Enriched Cell Populations | |||||||||||||
Chivu et al. | In vitro hepatic differentiation of human bone marrow mesenchymal stem cells under differential exposure to liver-specific factors | |||||||||||||
Nagai et al. | Differentiation of liver epithelial (stem-like) cells into hepatocytes induced by coculture with hepatic stellate cells | |||||||||||||
Crosby et al. | Human hepatic stem-like cells isolated using c-kit or CD34 can differentiate into biliary epithelium | |||||||||||||
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